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Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females
AbstractStress is a potent etiological factor in the onset of major depressive disorder and posttraumatic stress disorder (PTSD). Therefore, significant efforts have been made to identify factors that produce resilience to the outcomes of a later stressor,...
How To Feel A Little Less Alone During The Holidays
Expert tips for when grief, family issues or distance from loved ones make the holidays unbearable.The holidays are about being with your loved ones and celebrating with friends and family. But this time of the year can also be challenging for people who...
In Case You Missed It: Theta Burst Stimulation is Now FDA Approved
MagVenture, Inc: FDA Clears 3-Minute, Non-Pharmaceutical Depression TreatmentATLANTA, GA, Aug. 22, 2018 /CNW/ - For people suffering from severe depression, the road to remission just became a lot shorter: The treatment is known as Transcranial Magnetic...
Identifying Ketamine Responses in Treatment-Resistant Depression Using a Wearable Forehead EEG
Cao Z, Lin CT, Ding W, Chen MH, Li CT, Su TP.AbstractThis study explores the responses to ketamine in patients with treatment-resistant depression (TRD) using a wearable forehead electroencephalography (EEG) device. We recruited 55 outpatients with TRD who...
Ketamine, A Promising Depression Treatment, Seems To Act Like An Opioid
A new study suggests that ketamine, an increasingly popular treatment for depression, has something in common with drugs like fentanyl and oxycodone.The small study found evidence that ketamine’s effectiveness with depression, demonstrated in many small...
Study Shows Ketamine Reduces Obsessive Compulsive Behavior in Rats
This study from the National Institute of Health shows that "ketamine reduces compulsive behaviors in rats, showing effect in the orbitofrontal area".AbstractS-ketamine reduces marble burying behaviour in rats: Involvement of ventromedial orbitofrontal...
How Ketamine Works to Alleviate Depression
I would like to explain a little how ketamine works. Many years ago, when I first heard of ketamine being used for depression, like many of you, I thought that it was a sham treatment, that all doctors were doing was getting people a high which didn't fix...
How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
“By positioning the left side of the coil close to the left dorsolateral prefrontal cortex (DLPFC), the H1 coil was used in a multisite study, leading to FDA approval for treatment-resistant depression. In this same position, the H1 coil was also explored...
Theta Burst Stimulation Enhances Connectivity of the Dorsal Attention Network in Young Healthy Subjects: An Exploratory Study
Abstract We examined effects of theta burst stimulation (TBS) applied over two distinct cortical areas (the right inferior frontal gyrus and the left superior parietal lobule) on the Stroop task performance in 20 young healthy subjects. Neural...
Ketamine ameliorates depressive-like behaviors by tPA-mediated conversion of proBDNF to mBDNF in the hippocampus of stressed rats.
Highlights: • The new evidence of ketamine ameliorates the depressive-like behaviors in stressed rats. • proBDNF/mBDNF ratio provide novel perspectives and potential targets for the development of effective therapeutic intervention for depression. • The...