
Transcranial Magnetic Stimulation (TMS) therapy is an innovative, FDA-approved treatment for depression that offers a drug-free alternative for patients whose symptoms haven’t responded to medications. At Cantera Psychiatry in San Antonio, we provide TMS therapy as part of a comprehensive, patient-centered approach to mental health care.
If you’re considering TMS, it’s natural to have questions about side effects and what to expect during treatment. This guide explains the potential side effects, their frequency, and how to manage them so you can make an informed decision about whether TMS therapy is right for you.
Understanding TMS Therapy
TMS uses highly focused magnetic pulses, similar in strength to an MRI, to stimulate a specific region of the brain called the dorsolateral prefrontal cortex, which plays a key role in regulating mood. Treatments are non-invasive, typically lasting 20–40 minutes per session, five days a week for six weeks. Most patients are able to drive themselves to and from sessions and return to their normal daily activities immediately afterward.
Unlike oral antidepressants, TMS does not carry risks of weight gain, sexual dysfunction, or cognitive impairment. Its side effects are generally mild, localized, and temporary, making it one of the safest treatments for depression available.
Common TMS Side Effects
While TMS is well-tolerated by most patients, understanding common side effects can help you feel prepared for your first sessions.
Headaches
Headaches are the most frequently reported side effect, affecting about 30% of patients during the initial sessions. They are typically mild, occurring shortly after treatment, and often improve within an hour. Over-the-counter pain relievers such as ibuprofen or acetaminophen are usually sufficient to manage discomfort.
Scalp Discomfort or Tingling
Approximately 25% of patients experience sensations like tapping, tingling, or mild pain at the treatment site. This occurs as the magnetic pulses stimulate the scalp and underlying muscles. Discomfort usually decreases after the first week as your scalp adjusts.
Jaw or Facial Muscle Twitching
Some patients notice minor muscle twitches or spasms in the face or jaw during treatment. These movements are harmless and indicate that the magnetic field is stimulating neural circuits as intended. Adjustments to coil placement can minimize any discomfort.
Fatigue
A few patients feel temporarily tired after a session. This mild fatigue typically resolves quickly and may reflect your brain’s natural response to stimulation and adaptation.
Tooth or Jaw Sensitivity
Less commonly, patients report short-term toothaches or jaw discomfort. This occurs in fewer than 10% of patients and can usually be managed by repositioning during the session.
Less Common and Rare Side Effects
Lightheadedness or Dizziness
A small number of patients may feel briefly lightheaded during or after treatment. Staying hydrated and maintaining regular meals can reduce this effect.
Sleep Changes
Some patients notice changes in sleep patterns, such as more vivid dreams, difficulty falling asleep, or needing extra rest. These effects usually stabilize as the brain adapts to TMS therapy.
Auditory Effects
The TMS machine produces loud clicking sounds, which is why ear protection is provided. Failure to wear earplugs can lead to temporary ringing in the ears or increased sensitivity to sound.
“TMS Dip”
A temporary worsening of mood or anxiety can occur during the first week of treatment for some patients. Symptoms typically improve as treatment continues and your brain adjusts to stimulation.
Rare But Serious Risks
Serious complications, such as seizures, are extremely rare, occurring in fewer than 3 cases per 100,000 treatments. TMS is not recommended for patients with metal implants in the head or upper body due to the risk of injury. Your provider will screen for these contraindications before treatment.
How Side Effects Change Over Time
Most TMS side effects occur during the first week and diminish as treatment progresses. By the second week, many patients notice significant improvement in comfort, and from weeks three through six, side effects are usually minimal or absent. Individual experiences may vary depending on scalp sensitivity, anxiety levels, and overall health.
Preparing for TMS Therapy to Minimize Side Effects

Proper preparation can help reduce discomfort and make your TMS sessions smoother.
Medical and Physical Preparation
- Complete a thorough health screening with your provider, including a review of medications and any history of seizures or neurological conditions.
- Get adequate sleep the night before each session.
- Stay hydrated and eat a light meal prior to treatment.
- Wear comfortable clothing that allows easy access to your head and neck.
Mental and Emotional Preparation
- Learn about the TMS process in advance to reduce anxiety.
- Practice relaxation techniques such as deep breathing or mindfulness.
- Ask questions and set realistic expectations about side effects and treatment outcomes.
During and After Sessions
- Communicate openly with your provider about any discomfort.
- Always wear ear protection to prevent hearing issues.
- Manage minor headaches with over-the-counter pain relievers.
- Maintain hydration, nutrition, and a regular sleep schedule.
Comparing TMS Side Effects to Other Depression Treatments
| Treatment | Common Side Effects | Weight Changes | Sexual Function | Cognitive Effects | Recovery Time |
| TMS Therapy | Mild headache, scalp discomfort, temporary fatigue | None | None | None | Immediate return to daily activities |
| Antidepressants | Nausea, dizziness, fatigue | 10–25 lbs average gain | 40–60% experience dysfunction | Brain fog, emotional blunting | No recovery needed |
| ECT | Confusion, muscle aches | Variable | Minimal | Memory loss, confusion | Post-anesthesia recovery required |
TMS therapy offers the most favorable side effect profile of these options, with minimal, temporary effects and no impact on daily functioning or overall health.
Managing Side Effects: Practical Tips
Most TMS side effects are mild and manageable with simple strategies:
Headaches
- Over-the-counter pain relievers (ibuprofen, acetaminophen)
- Cool compresses on forehead or temples
- Gentle neck and shoulder stretches
Scalp Discomfort
- Gentle hair care with mild shampoo
- Avoid harsh styling products
- Position adjustments during treatment
Sleep Changes
- Keep a consistent sleep schedule
- Create a relaxing bedtime routine
- Limit caffeine and screen time before bed
Professional Support
- Always inform your provider if side effects worsen or new symptoms appear
- Providers can adjust coil placement, stimulation intensity, or session timing as needed
Long-Term Safety and Monitoring
TMS therapy has been used safely for over two decades, with extensive research supporting its excellent safety profile. Long-term studies show:
- No brain tissue damage or tumor formation
- No lasting cognitive impairment
- No increased risk of neurological disorders
At Cantera Psychiatry, your treatment is continuously monitored for safety, with ongoing follow-up to track your progress and address any delayed effects.
Making an Informed Decision
Understanding TMS side effects is an important step toward making an informed treatment decision. While every medical intervention carries some risk, TMS therapy’s mild, temporary, and manageable side effects, combined with its proven effectiveness for treatment-resistant depression, make it a safe option for many patients.
If you’re considering TMS therapy in San Antonio, Cantera Psychiatry offers expert care, personalized protocols, and comprehensive monitoring to ensure your comfort and safety throughout treatment.
Explore TMS Therapy in San Antonio
Being informed about potential side effects allows you to approach TMS therapy with confidence and realistic expectations. If you’re ready to explore whether TMS could be right for you, Cantera Psychiatry provides consultations to assess eligibility, answer questions, and guide you through each step of the treatment process.Take the first step toward learning more about this innovative, non-invasive approach to depression. Contact Cantera Psychiatry in San Antonio today to schedule a consultation and get answers tailored to your needs.
